Rapid reverse phase-HPLC assay of HMG-CoA reductase activity

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Rapid RP-HPLC assay of HMG-CoA reductase activity. AUTHORS

Radioisotope-based and mass spectrometry coupled to chromatographic techniques are the conventional methods for monitoring HMG-CoA reductase (HMGR) activity. Irrespective of offering adequate sensitivity, these methods are often cumbersome and time-consuming, requiring the handling of radiolabeled chemicals or elaborate ad-hoc derivatizing procedures. We propose a rapid and versatile RP-HPLC me...

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ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 2010

ISSN: 0022-2275

DOI: 10.1194/jlr.d006155